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Aled Edwards : ウィキペディア英語版
Aled Edwards

Aled Edwards (born June 1, 1962) is the director and CEO of the Structural Genomics Consortium and holds the Banbury Chair of Medical Research at the University of Toronto, Canada and is Visiting Professor of Chemical Biology at the University of Oxford, U.K.
==Scientific contributions==
Edwards and collaborators have focused on determining the three-dimensional structures of proteins encoded by human and microbial genomes. He and his colleagues have contributed over 2,000 entries into the Protein Data Bank. Notable structures include that of RNA polymerase II, human replication protein A, the Epstein-Barr virus Nuclear Antigen 1, the bacterial magnesium channel CorA, ZMPSTE24, a membrane protease mutated in people with progeria. The structural output includes over 1,000 different human proteins, which as of June 2012 accounted for ~15% of the structural coverage of the human proteome.
As the Structural Genomics Consortium, Edwards and colleagues in academia and industry have been using the wealth of structural information to guide the synthesis of chemical probes. These have been used to explore the links between epigenetics and disease and to identify drug targets in neglected diseases.

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